This is the text of my keynote speech at the 34th Chaos Communication Congress in Leipzig, December
Cells Weekly is posted every Sunday night!
This letter is warning company for many reasons, but two major are the following: The letter was issued on August 17 and it gives only 15 days for response. Apparently, company response was not satisfactory and FDA may order to cease operation I was not able to find documented proof of it.
There were shortcomings in how the decisions about the transplants were made and how they acted on existing laws. The hospital has a big task ahead to ensure patient safety and trust.
Read more details on For Better Science blog: The Asplund report found gross violations of medical ethics, patient right, even recruitment processes when analysing the history of the scandal around the Italian surgeon.
The affair has damaged trust in clinical research in Sweden, says the report, but the hospital is already taking steps to improve things.
For example, it has prepared internal guidelines for experimental clinical methods and for how to deal with whistle-blowers.
The KI will publish its own report on the case on 5 September. Macchiarini and his lawyer declined to comment on the latest report. Credit for discovery of medical optogenetics Anna Vlasists by STAT News wrote a great piece about development of medical optogenetics field and its pioneers.
The major theme of her article is who should be credited for key discoveries and pioneering the field. We all know that Karl Deisseroth and Ed Boyden are widely credited as pioneers, but another researcher — Zhuo-Hua Pan, conducted key experiments first.
The editors at Nature suggested they send it on to a more specialized journal called Nature Neuroscience, which rejected it.
Early the next year, Pan sent the paper to the Journal of Neuroscience, where it was reviewed but then again rejected. He may never know the answer. In her response, the editor replied that while the papers were similar, Boyden et al. Anna Vlasists discusses the problem with delaying of publications and crediting scientists for discoveries.
As for the invention itself, some scientists say Pan may not have had the big, award-worthy vision that Deisseroth and Boyden had. Asked whether he deserves the recognition that Boyden and Deisseroth have enjoyed, Pan declined to answer.
We would have gotten more credit. Role of hematopoietic stem cells in steady state hematopoiesis It is remain not very clear if all blood cell types are developed from one hematopoietic stem cell HSC in normal hematopoiesis, because of limitations of conventional transplantation models.
In these models, host bone marrow severely damaged by lethal irradiation and donor cells can skew hematopoietic repopulation in toxic marrow environment.
Recent studies, challenged significant contribution of HSCs in immune reconstitution.
Results of very recent study, which used more appropriate model of steady state hematopoiesis, were published in Immunity. Inducible genetic labeling showed that transgene-expressing HSCs gave rise to other phenotypic HSCs, confirming their top position in the differentiation hierarchy.
The labeled HSCs rapidly contributed to committed progenitors of all lineages and to mature myeloid cells and lymphocytes, but not to B-1a cells or tissue macrophages. Accelerated aging of immune system after hematopoietic stem cell transplantation Researchers demonstrated that hematopoietic stem cell transplantation in patients with hematological malignancies significantly accelerates aging of immune system.
They measured aging marker p16 on blood cells before and after of chemotherapy with hematopoietic stem cell transplantation. Turns out that expression of this aging marker on T-cells was significantly higher after transplant.
Effect was especially profound in autologous transplant and in patient with more cycles of chemotherapy. The senior author said: What is important about this work, however, is that it allows us to quantify the effect of stem cell transplant on molecular age. Cancer stem cell database Overview of new public database for identification of characterization of cancer stem cell is described this week in Stem Cells TM.
Herein, we describe the Cancer Stem Cells Therapeutic Target Database CSCTTthe first online database to provide a rich bioinformatics resource for the display, search, and analysis of structure, function, and related annotation for therapeutic targets of cancer stem cells.
CSCTT contains proteins that are potential targets of CSCs, with validated experimental evidence manually curated from existing literatures.Here is the gist of a question that I replied to in another forum. Q: Can someone advise a conversion method for phone number formats?
I have (many!) phone numbers in multiple formats and I would like to convert them all to numbers for comparison. Analysing Result Graphs This graph shows the range of ages of the people that I surveyed.
The majority was split evenly between the . David Lappi is a geologist from Alaska who has sent in a set of beautiful graphs–including an especially prosaic one of the last 10, years in Greenland–that he .
This graph shows the range of ages of the people that I surveyed. The majority was split evenly between the 30 – 40 age group and the 40 – 50 age group.
Bar graphs using different-sized intervals to represent numerical values (such as the above image) make true comparisons between groups more difficult. (However, the government probably has its reasons for reporting the numbers this way; for example, this may be the way income is broken down for tax-related purposes.).
IELTS task 1 resources with lessons and materials for tables, graphs, charts and process diagrams.